Treponemal Disease (Other Keyword)

DOCUMENT Citation Only Sarah Mathena. Molly K. Zuckerman. Nicholas P. Herrmann. Toni J. Copeland.

There are numerous historical, bioarchaeological, and paleopathological studies of treponemal disease, but most have focused on the origin and antiquity of syphilis. Therefore, little is known about the evolution and ecology of the other treponematoses, such as yaws. In modern populations, research options are limited by difficulty in culturing the causal bacteria, lack of animal models, and ethical issues with human testing. Treatment with antibiotics has also limited clinical research into...