metagenomics (Other Keyword)
1-2 (2 Records)
The trypanosomatid parasites are responsible for devastating human disease worldwide. In the Americas, Trypanosoma cruzi is the causative agent of Chagas Disease (CD), the most epidemic zoonosis in Latin America today. The clinical manifestations of CD, however, have been recognized in archaeological human remains from South America as early as 9,000 years ago. We present preliminary results of a project that applies paleogenomic methods, including targeted enrichment and next-generation...
An empty gut: the recent loss of our microbial symbionts (2016)
The increasing connectedness of global human populations during the Anthropocene has spread microbial pathogens far and wide. Yet at the same time, the human gut microbiome has simplified, leaving industrialised societies with less complex and diverse microbiota, and increased risk for chronic inflammatory disorders. Among the many taxa that have been lost is the bacterial genus Treponema. Treponema are present in the gut microbiota of great apes, present day hunter-gatherers in Africa and South...