human physiology (Other Keyword)

DOCUMENT Citation Only Lorna Moore.

The question of whether human populations have adapted genetically to high altitude (HA) has been of interest since studies began there in the early 1900s. Throughout the 20th century the dominant paradigm was that the major physiological attributes of HA residents were acquired during development or reflected other shorter-term processes. With the advent of genomic technologies and statistical methods for detecting genetic evidence of natural selection, a paradigm shift and an exponential rise...